2F-NENDCK HCl

Description

Advanced Research with 2F-NENDCK HCl (2-FXE)

2F-NENDCK, or 2-fluoro-N-ethylnordeschloroketamine, is a prominent research chemical within the arylcyclohexylamine family. It is chemically defined as the 2-fluoro analogue of O-PCE, featuring a fluorine atom at the ortho position of the phenyl ring. In specialized research settings, 2F-NENDCK serves as a primary subject for investigating the “ortho-fluorine effect”—studying how the replacement of a chlorine atom with a fluorine atom alters the compound’s lipophilicity, metabolic resistance, and binding kinetics at the NMDA receptor complex.

As an $N$-ethyl derivative with a ketone group at the 2-position of the cyclohexyl ring, 2F-NENDCK provides essential data for researchers mapping the electronic requirements of ligand-binding sites. When you buy 2F-NENDCK HCl in the USA through USA Professor, you are sourcing a professional-grade reagent refined for high-fidelity structural profiling, GC-MS calibration, and repeatable experimental data.

Technical Integrity & Laboratory Storage

• Structural Optimization: 2F-NENDCK features a 2-fluoro substitution, offering a unique platform for investigating the steric and electronic effects of halogenation on the arylcyclohexylamine core.

• Verified Analytical Purity: Our 2F-NENDCK is rigorously batch-tested to meet a purity standard of >98%, ensuring a clean profile for HPLC, GC-MS, and NMR spectroscopy.

• HCl Salt Stability: Provided in the stable hydrochloride salt form, this crystalline reagent is optimized for consistent measurement and long-term laboratory storage.

• Optimal Stability: 2F-NENDCK remains chemically stable for up to 2 years when stored in the correct environment. Like all arylcyclohexylamines, it is sensitive to heat and moisture. Store in a cool, dry, and dark location in an airtight container to maintain chemical integrity.

• Rapid USA Fulfillment: Avoid the logistical complexities and risks associated with international chemical shipping. All orders are processed and dispatched from our domestic USA facility, ensuring a secure and efficient supply chain for your research laboratory.

Technical Specifications

• Full IUPAC Name: 2-(ethylamino)-2-(2-fluorophenyl)cyclohexan-1-one

• Synonyms: 2-FXE, CanKet, 2fnendck, 2-fluoro-N-ethylnordeschloroketamine, 2′-Fluoro-2-Oxo-PCE

• CAS Number: 2850352-64-4

• Molecular Formula: $C_{14}H_{18}FNO \cdot HCl$

• Molar Mass: 235.302 g/mol (Base)

• Purity: >98%

Laboratory Safety & Handling Protocols

Warning: This product is intended strictly for laboratory research and forensic applications only. It is not for human or animal consumption.

• Inhalation: In the event of accidental inhalation, move the subject to fresh air immediately and ensure they remain in a position comfortable for breathing.

• Eye Contact: If the material enters the eyes, rinse gently with water for at least five minutes. Remove contact lenses if present and easy to do.

• Skin Contact: Wash the affected area thoroughly with soap and water. Use appropriate PPE, including gloves and lab coats, during all handling procedures.

• Environmental Responsibility: Discharge of research chemicals into the environment is prohibited. Dispose of all waste and residues in accordance with federal, state, and local hazardous material regulations.